This book reviews the role of randomized controlled trials (RCTs) in clinical dentistry, explains how to successfully conduct RCTs related to dentistry, and provides detailed information on the use of RCTs within each of the dental specialties. Although RCTs represent the gold standard in evidence-based dentistry for evaluation of the effects of an intervention, a textbook on the subject has to date been lacking. Randomized Controlled Trials in Evidence-Based Dentistry will fill this educational gap and improve the confidence of dental providers, researchers, and their multidisciplinary teams in conducting high-quality RCTs in a variety of settings and different parts of the world. In particular, it will enable readers to implement a suitable step-by-step approach to RCTs, identify possible solutions to common challenges when performing RCTs in individual dental specialties, and apply these solutions to their own RCT projects.